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KMID : 0381219790110030001
Journal of RIMSK
1979 Volume.11 No. 3 p.1 ~ p.6
Clinical Application of Maximal Expiratory Flow-volume Curve


Abstract
The clinical significance of maximal expiratory flow-volume curve(MEFV) was reviewed,. Previous analysis of the physiologic basis of the forced expiratory spirogram indicated that the MEFV curve contains the same information as the volume-time plot.
However, the MEFV curve is able to make an early diagnosis of emphysema and disease of small airways.
In early obstructive airway diseases, pathology. may be limited to peripheral airways
Analysis of flow at low lung volume is therefore diagnostically. important. , The flow volume loop is a ventilatory test easy to be demonstrated. Also -analysis. of peak flow rate at 25%, 50% and 75% of forced vital capacity must be, done.
Recently many reports emphasized the importance of. early detection of small airway diseases. They demontstrated reversibility of phisiologic abnormality by cessation of cigarette? smoking and by bronchodilator therapy.
Since advances in management off obstructive lung disease may.depend on early diagnosis,. it is important to develop simple nonivasive and accurate tests.
At present, analysis of MEFV curve and closing volume_ are. two tests that may be useful in the early detection of obstruction in small airways.
However, the M.EFV curve more readily allows quantitative analysis of flow at both high and¢¥ low volumes during forced exhalation, but from a careful analysis of the curves flow at 75% of forced vital captivity as well as its ratio to flow at 50% of forced vital capacity was found to be sensitive for detection of airway obstruction to a mild degree.
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